Membrane Disorders of Escherichia coli Cells and Liposomes Induced by p-Hydroxybenzoic Acid Esters
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چکیده
منابع مشابه
The effect of sorbic acid and esters of p-hydroxybenzoic acid on the protonmotive force in Escherichia coli membrane vesicles.
The effect of three food preservatives, sorbic acid and methyl and butyl esters of p-hydroxybenzoic acid, on the protonmotive force in Escherichia coli membrane vesicles was investigated. Radioactive chemical probes were used to determine the two components of the protonmotive force: delta pH (pH difference) and delta psi (membrane potential). Both types of compound selectively eliminated delta...
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p-Aminobenzoic acid (PABA) exerts three metabolic effects on E. coli: it acts as a normal vitamin at low concentrations, as a source of another vitamin, p-hydroxybenzoic acid (POB), at moderate concentrations, and as a growth inhibitor at high concentrations (150 to 1600 microg./ml.). The inhibition is competitively reversed by POB in 1/100 the concentration of PABA. The inhibition is also reve...
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Glycosylated p-hydroxybenzoic acid methyl esters and structurally related phenolphthiocerol glycolipids are important virulence factors of Mycobacterium tuberculosis. Although both types of molecules are thought to be derived from p-hydroxybenzoic acid, the origin of this putative biosynthetic precursor in mycobacteria remained to be established. We describe the characterization of a transposon...
متن کاملMetabolism of parabens (4-hydroxybenzoic acid esters) by hepatic esterases and UDP-glucuronosyltransferases in man.
Parabens (alkyl esters of 4-hydroxybenzoic acid) are widely used as preservatives in drugs, cosmetic products, and foodstuffs. Safety concerns have recently increased due to the potential health risks associated to exposure to large amounts of these substances. Biotransformation of parabens mainly includes hydrolysis of the ester bond and glucuronidation reactions. The hydrolysis and glucuronid...
متن کاملProtection against butyl p-hydroxybenzoic acid induced oxidative stress by Ocimum sanctum extract in mice liver.
Prime focus of the present investigation was to evaluate hepatoprotective potency of Ocimum sanctum (O. sanctum) aqueous extract against butyl p-hydroxybenzoic acid (butylparaben) toxicity in mice. Oral treatment of butylparaben (1320 mg/kg b.w./day) to mice for 30 days resulted in significant (p < 0.05) elevation in hepatic lipid peroxidation, which could be due to significant (p < 0.05) reduc...
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ژورنال
عنوان ژورنال: Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)
سال: 1991
ISSN: 0015-6426,1882-1006
DOI: 10.3358/shokueishi.32.121